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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
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[CADASIL syndrome: differential diagnosis with multiple sclerosis]
I Yu Danchenko1, A A Kulesh2, V E Drobakha2
1Perm Regional Clinical Hospital, Perm Multiple Sclerosis Center, Perm, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|January 15, 2020
Summary
Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) can be misdiagnosed as multiple sclerosis in young women. Early recognition of CADASIL
Area of Science:
- Neurology
- Radiology
- Genetics
Background:
- Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a rare genetic condition.
- It affects small blood vessels in the brain, leading to neurological symptoms.
Observation:
- Presents two cases of CADASIL in women under 40.
- Clinical and MRI findings were initially misinterpreted as multiple sclerosis.
- Highlights a lack of awareness among clinicians.
Findings:
- CADASIL shares some clinical and neuroimaging features with multiple sclerosis.
- Genetic verification is crucial for accurate diagnosis.
- Literature review covers diagnostic challenges and treatment.
Implications:
- Emphasizes the need for increased awareness of CADASIL among neurologists and radiologists.
- Improved diagnostic strategies are required for timely intervention.
- Understanding the clinical and neuroimaging patterns aids in patient management.
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