Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The rationale for pharmacologic cavernosography.

C G Stief1, F Benard, W Diederichs

  • 1Department of Urology, University of California, San Francisco 94143.

The Journal of Urology
|December 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic phenotypic shifts and M2 receptor downregulation in bladder smooth muscle cells induced by mirabegron.

Frontiers in pharmacology·2024
Same author

[Urinary diversion for acute epididymitis : Transurethral or suprapubic catheter?]

Urologie (Heidelberg, Germany)·2022
Same author

[Enhanced Recovery After Surgery (ERAS®) after radical cystectomy-current data].

Der Urologe. Ausg. A·2021
Same author

<sup>18</sup>F-PSMA-1007 PET/CT for response assessment in patients with metastatic renal cell carcinoma undergoing tyrosine kinase or checkpoint inhibitor therapy: preliminary results.

European journal of nuclear medicine and molecular imaging·2020
Same author

[The role of the microbiome in urology].

Der Urologe. Ausg. A·2020
Same author

[The microbiome in benign prostatic hyperplasia].

Der Urologe. Ausg. A·2020
Same journal

On the Memoryless Property in Markov Models for NMIBC Cost-Effectiveness Analysis.

The Journal of urology·2026
Same journal

Multi-institutional Assessment of Performance Metrics for MRI-targeted Transperineal Prostate Biopsy.

The Journal of urology·2026
Same journal

Urinary Supersaturation in a Randomized Trial among Individuals with Recurrent Nephrolithiasis comparing Empiric versus Selective Preventive Therapy: The URINE Trial.

The Journal of urology·2026
Same journal

The FDA Should Allow More BCG Strains into the US Market: How Recent Landmark Trials Expose a Regulatory Paradox.

The Journal of urology·2026
Same journal

Let's Shift the Focus from Death to Life after Fournier's Gangrene.

The Journal of urology·2026
Same journal

Endourology and Nephrolithiasis.

The Journal of urology·2026
See all related articles

Saline-induced cavernosography is not useful for diagnosing venogenic impotence. Pharmacocavernosography, which mimics natural erection, is recommended for identifying abnormal venous drainage in erectile dysfunction.

Area of Science:

  • Urology
  • Andrology
  • Vascular Physiology

Background:

  • Venogenic impotence is often diagnosed using cavernosography.
  • Current diagnostic methods may not accurately reflect physiological erectile function.

Purpose of the Study:

  • To evaluate the diagnostic efficacy of different cavernosography methods for venogenic impotence.
  • To identify the most reliable technique for detecting aberrant venous drainage.

Main Methods:

  • An experimental study was conducted on eight monkeys.
  • Cavernosography was performed after inducing erections via saline perfusion, neurostimulation, and papaverine injection.
  • Artificial cavernous leaks were created to assess pressure dynamics.

Main Results:

Related Experiment Videos

  • Saline-induced cavernosography consistently showed significant cavernous vein drainage, regardless of induced erection quality.
  • Neurostimulation or papaverine-induced erections did not visualize cavernous drainage, even with induced leaks.
  • Saline perfusion overestimates venous outflow, obscuring diagnostic findings.

Conclusions:

  • Cavernosography during saline-induced erection lacks diagnostic value for venogenic impotence.
  • Pharmacocavernosography effectively mimics the physiological venous occlusive mechanism.
  • Pharmacocavernosography is the preferred method for identifying abnormal venous drainage in erectile dysfunction.