Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

6.3K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
6.3K
Methods of reducing fever01:22

Methods of reducing fever

1.1K
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
1.1K
Decreased Body Temperature01:29

Decreased Body Temperature

917
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
917

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of a clinical engagement targeted antimicrobial stewardship program on antimicrobial use in Pakistan: a multicenter longitudinal point prevalence survey.

Expert review of anti-infective therapy·2026
Same author

The consequences of <i>Shigella</i> medically-attended diarrhoea and other leading pathogens among young children living in high-burden settings: a multi-country prospective cohort study.

EClinicalMedicine·2026
Same author

Frequency and correlates of non-receipt of age-appropriate vaccination among children aged 6-35 months with medically attended diarrhea: Findings from the Enterics for Global Health (EFGH) Shigella study, 2022-2024.

PLOS global public health·2026
Same author

Pullback pressure gradients: Redefining the functional landscape of coronary artery disease.

Cardiovascular revascularization medicine : including molecular interventions·2026
Same author

The feasibility of promoting recreational physical activity to manage type 2 diabetes in urban Bangladesh: A qualitative study.

Global public health·2026
Same author

Coronary septic embolism presenting as acute myocardial infarction: A rare manifestation of infective endocarditis: a case report.

European heart journal. Case reports·2026

Related Experiment Video

Updated: Dec 31, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.4K

Co-encapsulating CoFe2O4 and MTX for hyperthermia.

Nada Saleh1, Naveed Ahmed2, Muhammad Imran Asad2

  • 1Polymer Research Lab, Department of Materials Engineering, School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), NUST H-12 Campus, Islamabad 44000, Pakistan.

IET Nanobiotechnology
|January 15, 2020
PubMed
Summary

This study developed magnetic manotheranostics (MRPCs) for targeted cancer therapy. These MRPCs enable MRI diagnosis and hyperthermia treatment, minimizing healthy tissue damage from chemotherapy.

More Related Videos

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

2.8K
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
07:47

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Published on: December 13, 2015

9.4K

Related Experiment Videos

Last Updated: Dec 31, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.4K
Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

2.8K
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
07:47

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Published on: December 13, 2015

9.4K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Engineering

Background:

  • Magnetic manotheranostics offer dual diagnostic and therapeutic capabilities.
  • Chemotherapy can cause significant damage to healthy tissues.
  • Developing targeted drug delivery systems is crucial for improving cancer treatment efficacy.

Purpose of the Study:

  • To synthesize and characterize magnetically responsive polymer colloids (MRPCs) for cancer theranostics.
  • To evaluate the potential of MRPCs for MRI-guided diagnosis and hyperthermia treatment.
  • To assess the drug release profile and magnetic hyperthermia performance of the developed MRPCs.

Main Methods:

  • MRPCs were formulated using an oil-in-water emulsion technique with methotrexate (MTX) drug, Eudragit E100, and CoFe2O4 nanoparticles.
  • Formulations were optimized by adjusting constituent concentrations and sonication cycles.
  • Characterization included morphology, size (23-25 nm), surface charge, magnetic properties, and drug release studies at pH 7.4.

Main Results:

  • Synthesized MRPCs exhibited optimal characteristics for magnetic theranostics.
  • Drug release studies showed sustained release over 48 hours.
  • Magnetic hyperthermia tests demonstrated MRPCs' ability to reach therapeutic temperatures (42°C).

Conclusions:

  • The developed MRPCs show promise as a dual-action theranostic agent for cancer treatment.
  • MRPCs can potentially reduce chemotherapy side effects through targeted delivery and hyperthermia.
  • Further research is warranted to explore their clinical applicability in cancer therapy.