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Updated: Dec 31, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

474

Admission Hyperglycemia as a Predictor of Mortality in Acute Heart Failure: Comparison between the Diabetics and

Jae Yeong Cho1, Kye Hun Kim1, Sang Eun Lee2

  • 1Department of Cardiovascular Medicine, Chonnam National University Medical School/Hospital, 42 Jebong-ro, Dong-gu, Gwangju 61469, Korea.

Journal of Clinical Medicine
|January 16, 2020
PubMed

Insights

Admission hyperglycemia predicts in-hospital death and 1-year mortality in acute heart failure patients. This risk is independent of diabetes mellitus, highlighting the need for close monitoring in all affected individuals.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Acute heart failure (AHF) is a leading cause of mortality.
  • Hyperglycemia on admission (HGL) is common in AHF patients.
  • The impact of HGL on mortality in AHF, considering diabetes mellitus (DM), requires further investigation.

Purpose of the Study:

  • To investigate the impact of admission hyperglycemia (HGL) on in-hospital death (IHD) and 1-year mortality in acute heart failure (AHF) patients.
  • To compare these outcomes in AHF patients with and without diabetes mellitus (DM).

Main Methods:

  • A nationwide registry of 5625 AHF patients was analyzed.
  • 5541 patients were categorized into four groups based on admission HGL (> 200 mg/dL) and DM status.
  • In-hospital death (IHD) and 1-year mortality were compared across groups.

Main Results:

  • Admission HGL was a significant predictor of both IHD (7.6% vs. 4.2%) and 1-year mortality (26.2% vs. 21.3%).
  • DM predicted 1-year mortality (24.8% vs. 20.5%) but not IHD.
  • Admission HGL independently predicted 1-year mortality in non-DM patients (HR 1.32).

Conclusions:

  • Admission HGL is a significant predictor of IHD and 1-year mortality in AHF patients.
  • While DM predicts 1-year mortality, HGL impacts both IHD and 1-year mortality, particularly in non-DM patients.
  • Close monitoring and intensive therapy are recommended for AHF patients with admission HGL, irrespective of DM status.
Abstract

Keywords:
acute heart failurediabetes mellitushyperglycemiamortality

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