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Updated: Dec 30, 2025

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
HIV-related nephropathy: new aspects of an old paradigm
Érica Lofrano Reghine1, Renato Demarchi Foresto2, Gianna Mastroianni Kirsztajn1
1Departamento de Medicina (Nefrologia) da Universidade Federal de São Paulo, São Paulo, SP, Brasil.
Abstract:
The scenario of infection by the human immunodeficiency virus (HIV) has been undergoing changes in recent years, both in relation to the understanding of HIV infection and regarding the treatments available. As a result, the disease, which before was associated with high morbidity and mortality, is now seen as a chronic disease that can be controlled, regarding both transmission and symptoms. However, even when the virus replication is well controlled, the infected patient remains at high risk of developing renal involvement, either by acute kidney injury not associated with HIV, nephrotoxicity due to antiretroviral drugs, chronic diseases associated with increased survival, or glomerular disease associated to HIV. This review will cover the main aspects of kidney failure associated with HIV.
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