PrEP Implementation Behaviors of Community-Based HIV Testing Staff: A Mixed-Methods Approach Using Latent Class...

Area of Science:

• Public Health
• Implementation Science
• HIV Prevention

Background:

• Pre-exposure Prophylaxis (PrEP) is a key HIV prevention strategy.
• Current PrEP uptake remains limited among at-risk populations.

Purpose of the Study:

• To identify subgroups of HIV testing staff based on PrEP discussion practices.
• To understand factors influencing PrEP implementation among these staff.

Main Methods:

• A mixed-methods design combining latent class analysis and thematic analysis.
• Investigated staff subgroups discussing PrEP in community-based HIV testing settings.
• Generalized linear mixed models analyzed PrEP implementation based on staff characteristics.

Main Results:

• Three distinct PrEP implementation groups were identified: Universal, Eligibility-dependent, and Limited.
• Staff race and sexual orientation were significant predictors of PrEP discussion groups.
• Minority staff were less likely to be in the 'Limited' discussion group.

Conclusions:

• HIV testing staff exhibit varied approaches to discussing PrEP with clients.
• Perceived client eligibility influences PrEP discussions for some staff.
• Tailored training interventions for specific PrEP implementation groups may enhance HIV prevention efforts.