Small Bowel Diverticulosis: Pathogenesis, Clinical Management, and New Concepts

Vikram Rangan1, J Thomas Lamont2

  • 1Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA. vrangan@bidmc.harvard.edu.

Abstract

Insights

Small bowel diverticulosis diagnosis has advanced with CT and MRI replacing barium studies. While asymptomatic cases require no intervention, endoscopy and surgery manage complications like bleeding and obstruction.

Area of Science:

  • Gastroenterology
  • Digestive Diseases

Background:

  • Small bowel diverticulosis is a recognized condition with evolving diagnostic and management strategies.
  • This review focuses on the pathophysiology, incidence, prevalence, and modern approaches to small bowel diverticulosis, excluding Meckel's diverticula.

Purpose of the Study:

  • To provide an updated review of small bowel diverticulosis.
  • To cover pathophysiology, incidence, prevalence, diagnosis, and management.

Main Methods:

  • Review of current literature on small bowel diverticulosis.
  • Focus on diagnostic imaging and therapeutic interventions.

Main Results:

  • Computed tomography (CT) scans and magnetic resonance imaging (MRI) are now preferred over barium follow-through for diagnosis.
  • Asymptomatic small bowel diverticulosis typically requires no intervention.
  • Endoscopic management is increasingly utilized for bleeding and intraduodenal diverticula resection.
  • Surgical intervention remains the primary treatment for complications such as diverticulitis and small bowel obstruction.

Conclusions:

  • Small bowel diverticulosis is uncommon but can lead to serious complications.
  • A high index of suspicion is crucial for timely diagnosis.
  • While endoscopy plays a growing role, surgical resection is the definitive treatment for most complications.

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
395
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
570
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
795
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
701
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
862
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
395