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Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
Published on: May 16, 2019
Chapter 4: Microelements: Part I: Zn, Sn, Cu, Fe and I
Richard J M Lynch1, Ralph M Duckworth2,3
1GSK Oral Healthcare, St. Georges Avenue, Weybridge, United Kingdom.
Microelements like zinc and tin show promise in preventing dental caries by inhibiting bacterial acid production and aiding enamel remineralization. Further research is needed to confirm the clinical efficacy of iodine and other microelements in oral hygiene.
Area of Science:
- Oral Health
- Nutritional Science
- Biochemistry
Background:
- Microelements are vital dietary components.
- Deficiencies can lead to health issues, necessitating supplements.
- Their role in oral health is complex due to low concentrations and interactions.
Purpose of the Study:
- To review the effects of zinc, copper, iron, tin, and iodine on oral health.
- To explore their impact on dental caries and related processes.
- To assess their potential in oral hygiene products and treatments.
Main Methods:
- Literature review of microelement effects on oral health.
- Analysis of studies on antibacterial properties and ion concentrations.
- Examination of research on de- and remineralization processes.
Main Results:
- Zinc and tin show significant potential in managing dental caries by affecting de- and remineralization.
- These elements, particularly zinc, can reduce enamel dissolution and inhibit calculus formation.
- Copper and iron demonstrate anti-caries effects in animal models, while iron reduces enamel erosion.
- Iodine exhibits broad-spectrum antibacterial properties, but clinical evidence for oral conditions is limited.
Conclusions:
- Zinc and tin are valuable in oral hygiene products due to their anti-caries properties.
- While other microelements show promise, more robust clinical validation is required, especially for iodine.
- Understanding microelement interactions is key to optimizing their oral health benefits.
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