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Updated: Dec 30, 2025
Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
Published on: April 7, 2017
Hydrophilic Porous Poly(l-Lactic Acid) Nanomembranes: Self-Assembly, and Anti-Biofouling and Anti-Thrombosis Effects
Xiulong Deng1, Mengbi Zhang2, Lishan Tan2
1Nanobiological Medicine Center, Key Lab of Fuel Cell Technology of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, P. R. China.
Abstract:
Hydrophilic PEGylated porous self-assembled nanomembranes (PSANMs) with average thickness and pore diameter of ca. 10 and 20-24 nm were successfully prepared by an emulsification-induced programmable self-assembly strategy. The hydrophilicity, anti-biofouling, and anti-thrombosis properties of PEGylated PSANMs were largely improved in comparison with the nonfunctionalized PSANMs, which could transform into hydrophilic (PEGylated PSANMs, minimum water contact angle: 38.8°) from hydrophobic units (PSANMs, maximum water contact angle: 137.5°) with increasing PEG density and length. The total protein adsorption of PEGylated PSANMs was about six times lower than that of the PSANMs, while the thrombosis of the PEGylated PSANMs (maximum R-time: 5.37 min) was also greatly relieved in comparison with the PSANMs (minimum R-time: 2.93 min). Such PEG-modified PSANMs may have applications in drug delivery and tissue and organ repair in vivo.
