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Published on: August 31, 2019
Recent Strategies in Resveratrol Delivery Systems
Noelia D Machado1,2, Mariana A Fernández1,2, David Díaz Díaz3,4
1Universidad Nacional de Córdoba Facultad de Ciencias Químicas Departamento de Química Orgánica, Ciudad Universitaria, X5000HUA, Cordoba, Argentina.
Resveratrol (RSV) has beneficial properties but faces bioavailability challenges. Recent advancements in nano and micro encapsulation are improving its use in nutrition and pharmaceuticals.
Area of Science:
- Biochemistry
- Pharmacology
- Materials Science
Background:
- Resveratrol (RSV) is a natural stilbenoid found in grapes and wine with known cardio-protective, antioxidant, and anti-inflammatory effects.
- Trans-resveratrol (RSV) is the most biologically active form, but its therapeutic potential is hindered by poor water solubility, low oral bioavailability, and chemical instability.
Purpose of the Study:
- To review recent advancements in carrier and delivery systems for resveratrol.
- To summarize the properties of various resveratrol delivery systems developed over the past five years.
Main Methods:
- Literature review of scientific publications from the last five years.
- Analysis of studies focusing on nano and micro encapsulation techniques for resveratrol.
- Evaluation of reported properties and effectiveness of different RSV delivery systems.
Main Results:
- Various nano and micro encapsulation strategies have been developed to enhance resveratrol's solubility and bioavailability.
- These advanced delivery systems aim to overcome the inherent limitations of RSV for improved efficacy.
- The review covers a range of carriers and delivery platforms investigated for nutritional and pharmaceutical applications.
Conclusions:
- Nano and micro encapsulation represent promising strategies to improve resveratrol's therapeutic and nutritional applications.
- Further research into optimized delivery systems is crucial for maximizing the benefits of resveratrol.
- Advanced delivery systems are key to unlocking the full potential of resveratrol in various fields.
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