Related Experiment Video
Updated: Dec 30, 2025
07:04
Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
13.9K
Adverse drug reactions in dentistry
Aviv Ouanounou1, Kester Ng2, Peter Chaban2
1Department of Clinical Sciences, Pharmacology & Preventive Dentistry, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.
International Dental Journal
|January 17, 2020
Summary
Adverse drug reactions (ADRs) can occur with dental medications. This review covers common dental drugs, their potential side effects, and management strategies for clinicians.
Area of Science:
- Pharmacology
- Dental Therapeutics
Background:
- Adverse drug reactions (ADRs) are unintended effects from medications used in dentistry.
- While most dental drugs are safe, clinicians must recognize and manage potential ADRs.
Purpose of the Study:
- To review common dental medications and their associated adverse drug reactions.
- To provide guidance on managing complications arising from these ADRs.
Main Methods:
- Literature review of commonly used dental agents.
- Analysis of reported adverse drug reactions and management protocols.
Main Results:
- Identified local anesthetics, sedatives, analgesics, and antibiotics as key drug classes.
- Detailed common ADRs for each drug class.
Conclusions:
- Awareness of potential ADRs is crucial for dental practitioners.
- Effective management strategies are essential for patient safety in dental settings.
More Related Videos
Related Concept Videos
01:25Pharmacokinetics: Drug–Drug Interactions
284
Drug interactions occur when the pharmacological effect of one drug is altered by another substance, either enhancing or diminishing its activity. The drug whose activity is altered is known as the object drug, and the substance causing the alteration is called the agent drug or the precipitant. The net effects of these interactions are mostly undesirable, leading to decreased effectiveness or increased adverse effects. In rare cases, interactions can be beneficial, such as the enhanced...
284
01:12Local Anesthetics: Adverse Effects
708
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
708
01:19Pharmacovigilance
1.5K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.5K
01:27Effects of Chemicals: Overview
1.9K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.9K
01:27Allergic Drug Reactions
1.3K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.3K
01:30Combined Effects of Drugs: Antagonism
11.4K
The combined effects of drugs can result in various interactions, of which an important type is antagonism. Antagonism is a mechanism where one drug inhibits or counteracts the effects of another drug. Antagonism can occur through various means, including receptor binding, allosteric modulation, functional interaction, chemical reactions, and pharmacokinetic processes.
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
11.4K