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Updated: Dec 30, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Photoinduced C(sp2)-H/C(sp2)-H Cross-Coupling of Alkenes: Direct Synthesis of 1,3-Dienes
Qi Xu1, Baihui Zheng1, Xiaoxuan Zhou1
1Jilin Province Key Laboratory of Organic Functional Molecules, Design & Synthesis, Department of Chemistry, Northeast Normal University, Changchun 130024, China.
Abstract:
A highly concise route to substituted 1,3-dienes from vinylarenes and ketene dithioacetals under photoinduced cross-coupling reaction is described. The reaction proceeded in a highly regio- and stereoselective manner and showed broad functional group tolerance. More than 35 substituted 1,3-dienes were synthesized with good to excellent yields through the construction of the Csp2-Csp2 bond without using noble metal and external oxidants, and natural sunlight could also induce the reaction to afford gram-scale synthesis under ambient conditions.
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