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Updated: Dec 30, 2025

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
HIV Outbreak Control With Effective Access to Care and Harm Reduction in North Carolina, 2017-2018
Erika Samoff1, Victoria Mobley1, Michelle Hudgins1
1Erika Samoff, Victoria Mobley, Michelle Hudgins, Nicole Dzialowy Adams, Christina R. Caputo, Christy A. Crowley, Jacquelyn M. Clymore, and Evelyn Foust are with the Communicable Diseases Branch, Epidemiology Section, North Carolina Division of Public Health, Raleigh, NC. Anna Barry Cope is with the Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA. Rachael M. Billock is with the Department of Epidemiology, Gillings Global School for Public Health, University of North Carolina at Chapel Hill. Ann M. Dennis is with the Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill.
Abstract:
Objectives. To assess and control a potential outbreak of HIV among people who inject drugs in Western North Carolina.Methods. Disease intervention specialists offered testing for hepatitis B and hepatitis C, harm reduction materials, and linkage to care to 7 linked people recently diagnosed with HIV who also injected drugs. Contacts were offered the same services and HIV testing. HIV genotype analysis was used to characterize HIV spread. We assessed testing and care outcomes by using state surveillance information.Results. Disease intervention specialists contacted 6 of 7 linked group members and received information on 177 contacts; among 96 prioritized contacts, 42 of 96 (44%) were exposed to or diagnosed with hepatitis C, 4 of 96 (4%) had hepatitis B, and 14 of 96 (15%) had HIV (2 newly diagnosed during the investigation). HIV genotype analysis suggested recent transmission to linked group members and 1 contact. Eleven of 14 with HIV were virally suppressed following the outbreak response.Conclusions. North Carolina identified and rapidly responded to an HIV outbreak among people reporting injecting drugs. Effective HIV care, the availability of syringe exchange services, and the rapid response likely contributed to controlling this outbreak.
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