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[Experimental and theoretical study of the dynamics of lymphopoiesis during prolonged irradiation]
Radiobiologiia
|September 1, 1988
Abstract:
A mathematical model has been developed describing the dynamics of lymphopoiesis in mammals chronically exposed to ionizing radiation: it is based on the chalone mechanism of regulation of the rate of bone marrow blast cell reproduction and represents a system of 9 nonlinear differential equations. The results of the mathematical simulation and experimental evidence have been found to agree within a wide range of dose rates.