Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

9.8K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enrichment of fetal cell-free DNA in early miscarriages for detection of aneuploidy: a novel approach.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

Scale-invariant brain morphometry: application to sulcal depth.

Computers in biology and medicine·2026
Same author

User Experience of a Virtual Reality-Based Treadmill for Children With a Chronic Disease Affecting Physical Health: Cross-Sectional Feasibility Study.

JMIR serious games·2026
Same author

Long-term impact of traumatic brain injury on informal caregivers: burden, quality of life and the role of time since injury.

Annals of physical and rehabilitation medicine·2026
Same author

Quantitative comparison of explainable AI methods for interpreting deep learning-based classification of 3D gait kinematics.

Scientific reports·2026
Same author

Validation of PREM-PS, a patient-reported experience instrument, in a randomized controlled trial of pregnant women undergoing prenatal screening.

Journal of patient-reported outcomes·2026

Related Experiment Video

Updated: Dec 30, 2025

Three-Dimensional Shape Modeling and Analysis of Brain Structures
05:33

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

7.5K

On early brain folding patterns using biomechanical growth modeling.

Xiaoyu Wang, Amine Bohi, Mariam Al Harrach

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 18, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Computational models reveal how mechanical forces influence brain folding, offering insights into neurodevelopmental disorders like lissencephaly. This study enhances brain models to better understand cortical folding and its relation to physical parameters.

    More Related Videos

    Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis
    06:33

    Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis

    Published on: June 5, 2018

    7.6K
    How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index
    09:57

    How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

    Published on: January 2, 2012

    28.4K

    Related Experiment Videos

    Last Updated: Dec 30, 2025

    Three-Dimensional Shape Modeling and Analysis of Brain Structures
    05:33

    Three-Dimensional Shape Modeling and Analysis of Brain Structures

    Published on: November 14, 2019

    7.5K
    Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis
    06:33

    Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis

    Published on: June 5, 2018

    7.6K
    How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index
    09:57

    How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

    Published on: January 2, 2012

    28.4K

    Area of Science:

    • Neuroscience
    • Computational Biology
    • Developmental Biology

    Background:

    • Abnormal cortical folding is linked to neurodevelopmental disorders such as lissencephaly and polymicrogyria.
    • Computational modeling aids understanding of early brain folding, with biomechanical models highlighting the role of mechanical forces.
    • Gaps exist in correlating simulation results with biological data and understanding the impact of physical parameters.

    Purpose of the Study:

    • To propose an improved brain growth model incorporating longitudinal length.
    • To investigate the influence of initial cortical thickness on brain folding patterns.
    • To enhance biomechanical models for understanding neurodevelopmental disorders.

    Main Methods:

    • Developed a new brain longitudinal length growth model.
    • Utilized biomechanical modeling to simulate cortical folding.
    • Quantified gyrification using surface-based 3D gyrification index and spectral analysis.

    Main Results:

    • The proposed model improves brain model growth.
    • Initial cortical thickness was found to affect folding patterns.
    • Biomechanical models show potential in linking physical parameters to neurodevelopmental diseases.

    Conclusions:

    • Biomechanical models are valuable tools for studying brain development.
    • Understanding the role of physical parameters can elucidate links to neurodevelopmental disorders.
    • Further research can refine these models for clinical applications.