Related Experiment Video
Updated: Dec 30, 2025
Laser Doppler: A Tool for Measuring Pancreatic Islet Microvascular Vasomotion In Vivo
Published on: March 8, 2018
Characterization of Microvascular Post Occlusive Hyperemia Using Laser Doppler Flowmetry Technique in Subjects With
Introduction:
Laser Doppler flowmetry (LDF) provides a noninvasive real-time quantification of relative changes in cutaneous perfusion. Assessment of the microvascular function can provide information on the development of various cardiometabolic disorders. In recent years, non-invasive measurements have gain attention, due to the potential complications associated to invasive procedures.
Objective:
To differentiate the microvascular function between subjects with cardiometabolic disorders and healthy controls.
Methods:
Evaluation through LDF during post-occlusive reactive hyperemia (PORH) in patients with or without history of cardiometabolic disorders.
Results:
Peak values of microvascular flow during post-occlusive reactive hyperemia and both upload and recovery slopes were lesser in the pathological group.
Conclusion:
A novel approach to characterize LDF during PORH was useful to differentiate patients with cardiometabolic disorders from healthy subjects.
