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Updated: Dec 30, 2025

Time-Resolved Fluorescence Anisotropy from Single Molecules for Characterizing Local Flexibility in Biomolecules
Published on: April 25, 2025
Influence of Tissue Anisotropy on Molecular Communication
Abstract:
Many biological tissues inside the human body exhibit highly anisotropic diffusion properties; for example, tissues of the nervous system and white matter in the brain. Here, we present an improved stochastic molecular communication framework to model interaction between bionanomachines in three-dimensional (3D) anisotropic brain micro-environment. The results obtained using stochastic particle-based simulation model are validated with analytical expressions. We also derive expressions for peak amplitude and peak time for the received molecular signal. The results demonstrate that the channel impulse response in anisotropic biological media depends significantly on the diffusion tensor as well as on the locations of the nanomachines.
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