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Updated: Dec 30, 2025

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
Published on: November 7, 2017
Enhanced ICMR amplifier for high CMRR biopotential recordings
Abstract:
This paper presents an integrated biopotential preamplifier architecture targeting applications that simultaneously require high common-mode rejection ratio (CMRR), low noise, high input common-mode range (ICMR), and current-efficiency (low Noise Efficiency Factor or NEF). A biopotential preamplifier, which performs well in line with the state-of-the-art of the field while providing enhanced ICMR and CMRR performance, was fabricated in a 0.5 μm CMOS process. Results from measurements show that the gain is 47 dB, the bandwidth ranges from 1 Hz to 7.7 kHz, the equivalent input noise is 1.8 μVrms, the CMRR is 100.5 dB, the ICMR is 1.7 V and the NEF is 3.2.

