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Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
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Exploring Characteristic Features in Gait Patterns for Predicting Multiple Sclerosis

Rachneet Kaur, Sanjana Menon, Xiaomiao Zhang

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 18, 2020
    PubMed

    Abstract:

    Multiple Sclerosis (MS), an autoimmune and demyelinating disease, is one the most prevalent neurological disabilities in young adults. It results in damage of the central nervous system, disrupting communication between the patient's brain, spinal cord and body. Mobility limitations is one of the earliest symptoms and affects a majority of persons with Multiple Sclerosis. We are working towards an effort to characterize individuals with MS, from those without, on the basis of variations in the gait patterns. In the proposed work, statistical methods were used to identify differentiating gait data features for MS characterization. The prediction algorithms built upon these characteristic features will help clinicians develop effective and early cure and therapy designs for persons with Multiple Sclerosis.

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    Multiple Sclerosis l: Introduction01:19

    Multiple Sclerosis l: Introduction

    Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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