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Published on: September 26, 2018
Cardiovascular disease diagnosis using cross-domain transfer learning
Insights
This study introduces a novel deep learning method for classifying cardiovascular diseases (CVDs) from electrocardiogram (ECG) signals. The approach leverages transfer learning and spectrograms for accurate, automated CVD detection.
Area of Science:
- Biomedical Engineering
- Artificial Intelligence in Medicine
- Cardiology
Background:
- Cardiovascular diseases (CVDs) diagnosis relies on electrocardiogram (ECG) interpretation, often manual.
- Automated CVD detection using ECGs faces challenges with feature generalization due to varying acquisition parameters.
- Current deep learning (DL) methods for ECG analysis require extensive data and computational resources for training from scratch.
Purpose of the Study:
- To develop an automated, data-driven approach for CVD classification from ECG waveforms.
- To overcome limitations of hand-crafted features and resource-intensive DL models.
- To propose an end-to-end trainable cross-domain transfer learning framework for CVD detection.
Main Methods:
- Utilized pre-existing Convolutional Neural Network (CNN) frameworks, originally designed for vision tasks, as feature extractors.
- Employed a stacked spectrogram representation of multi-lead ECG waveforms as a preprocessing step for CNN compatibility.
- Developed a fusion strategy for multiple ECG leads by stacking spectrograms to capture spatial relationships.
Main Results:
- Achieved competitive performance in CVD classification across multiple ECG datasets.
- Demonstrated the efficacy of cross-domain transfer learning for ECG analysis.
- Validated the proposed stacked spectrogram and multi-lead fusion approach.
Conclusions:
- The proposed cross-domain transfer learning method offers an efficient and effective approach for automated CVD classification from ECGs.
- This method addresses the limitations of traditional feature engineering and training deep learning models from scratch.
- The use of stacked spectrograms and lead fusion provides a robust way to encode ECG information for improved diagnostic accuracy.
Abstract:
While cardiovascular diseases (CVDs) are commonly diagnosed by cardiologists via inspecting electrocardiogram (ECG) waveforms, these decisions can be supported by a data-driven approach, which may automate this process. An automatic diagnostic approach often employs hand-crafted features extracted from ECG waveforms. These features, however, do not generalise well, challenged by variation in acquisition settings such as sampling rate and mounting points. Existing deep learning (DL) approaches, on the other hand, extract features from ECG automatically but require construction of dedicated networks that require huge data and computational resource if trained from scratch. Here we propose an end-to-end trainable cross-domain transfer learning for CVD classification from ECG waveforms, by utilising existing vision-based CNN frameworks as feature extractors, followed by ECG feature learning layers. Because these frameworks are designed for image inputs, we employ a stacked spectrogram representation of multi-lead ECG waveforms as a preprocessing step. We also proposed a fusion of multiple ECG leads, using plausible stacking arrangements of the spectrograms, to encode their spatial relations. The proposed approach is validated on multiple ECG datasets and competitive performance is achieved.
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