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Updated: Dec 30, 2025

Performing Subretinal Injections in Rodents to Deliver Retinal Pigment Epithelium Cells in Suspension
Published on: January 23, 2015
Design of an Integrated Subretinal Implant using Cellular Neural Networks for Binary Image Generation in a 130 nm
Abstract:
Blindness caused by the eye diseases Retinitis-Pigmentosa and Age-Related-Macular-Degeneration leads to a degeneration of the photoreceptor layer while postsynaptic cells mostly stay intact. In this Paper a new concept for retinal implants is proposed. Instead of converting the incident light to a gray-scale picture with corresponding continuous-value stimulation levels, we here suggest to produce a binary image picture that only highlight edges in order to stimulate the retina solely at points which belong to an edge. An integrated test circuit is designed with a 130 nm BiCMOS process by using cellular neural networks for binary image generation. The circuit yields a simulated maximum rated power consumption of 2.61 mW for a 1000 information processing cells.
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