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Lactobacillus iners-dominated vaginal microbiota in pregnancy.
Ceska Gynekologie
|January 18, 2020
Summary
Lactobacillus iners-dominated vaginal microbiota during pregnancy is linked to a higher risk of complications like abortion and preterm birth. This review summarizes current knowledge on this association.
Area of Science:
- Reproductive Health
- Microbiology
- Obstetrics
Background:
- The vaginal microbiota plays a crucial role in reproductive health.
- Lactobacillus species are key components of a healthy vaginal microbiome.
- Lactobacillus iners is a common but often less understood vaginal lactobacillus species.
Purpose of the Study:
- To review current scientific literature on Lactobacillus iners-dominated vaginal microbiota during pregnancy.
- To investigate the association between L. iners and adverse pregnancy outcomes.
Main Methods:
- A comprehensive literature review was conducted.
- Studies examining vaginal microbiota composition in pregnant individuals were analyzed.
- Data on pregnancy complications in relation to L. iners were synthesized.
Main Results:
- Lactobacillus iners-dominated vaginal microbiota is prevalent in some pregnant populations.
- Evidence suggests an association between L. iners dominance and increased risk of abortion.
- A link was observed between L. iners and spontaneous preterm delivery with intact membranes and preterm prelabor rupture of membranes.
Conclusions:
- Lactobacillus iners-dominated vaginal microbiota is associated with an elevated risk of specific pregnancy pathologies.
- Further research is warranted to understand the mechanisms underlying this association.
- Clinical monitoring may be beneficial for pregnant individuals with L. iners-dominated microbiota.
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