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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

213
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
213
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Venous Return01:04

Venous Return

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The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
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Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

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Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
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Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

157
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Heart Failure I: Introduction01:27

Heart Failure I: Introduction

617
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Related Experiment Video

Updated: Dec 30, 2025

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
07:41

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Incident Heart Failure and Long-Term Risk for Venous Thromboembolism.

Christina L Fanola1, Faye L Norby2, Amil M Shah3

  • 1Division of Cardiovascular Medicine, University of Minnesota Medical Center, Minneapolis, Minnesota.

Journal of the American College of Cardiology
|January 18, 2020
PubMed
Summary
This summary is machine-generated.

Heart failure (HF) significantly increases long-term risk for venous thromboembolism (VTE). This risk applies to both HF subtypes and is linked to structural heart changes, necessitating new prevention strategies.

Keywords:
deep venous thrombosisechocardiographyheart failurepulmonary embolismvenous thromboembolism

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Area of Science:

  • Cardiology
  • Vascular Medicine
  • Epidemiology

Background:

  • Hospitalization for heart failure (HF) is known to elevate short-term risk for venous thromboembolism (VTE).
  • The long-term VTE risk associated with incident HF, its subtypes, or underlying structural heart disease remained largely unknown prior to this study.

Purpose of the Study:

  • To assess the long-term risk of VTE in relation to incident heart failure (HF), different HF subtypes, and echocardiographic measures indicative of structural heart disease in the absence of clinical HF.
  • To investigate the association between HF, HF subtypes, and cardiac structural abnormalities with subsequent VTE events.

Main Methods:

  • Utilized the Atherosclerosis Risk In Communities (ARIC) cohort, including over 13,000 participants followed for a mean of 22 years.
  • Incident HF and VTE were identified through clinical examinations and hospital records, with HF categorized into preserved or reduced ejection fraction.
  • Adjusted Cox proportional hazards models were employed to analyze the associations between HF, HF subtypes, echocardiographic measures, and VTE risk.

Main Results:

  • Developed HF was associated with a significantly increased long-term risk of VTE (aHR: 3.13).
  • Both HF with preserved ejection fraction (aHR: 4.71) and HF with reduced ejection fraction (aHR: 5.53) demonstrated similar elevated long-term VTE risks.
  • In individuals without HF, specific echocardiographic findings like increased left ventricular relative wall thickness and mean wall thickness independently predicted VTE risk.

Conclusions:

  • Incident hospitalized heart failure, encompassing both preserved and reduced ejection fraction types, is linked to a substantially elevated long-term risk of VTE.
  • Echocardiographic indicators of left ventricular remodeling also predict increased long-term VTE risk, even in the absence of diagnosed HF.
  • There is a critical need for evidence-based strategies to prevent long-term VTE in patients with HF, extending beyond the hospitalization period.