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Updated: Dec 30, 2025

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
Reinforced Feedback in Virtual Environment for Plantar Flexor Poststroke Spasticity Reduction and Gait Function
Carlos Luque-Moreno1,2,3, Fátima Cano-Bravo3, Pawel Kiper1
1San Camillo IRCCS, Via Alberoni, 70, 30126 Lido di Venezia, Italy.
This study found that combining traditional rehabilitation with a reinforced feedback virtual environment (RFVE) effectively reduced ankle spasticity and improved gait function in stroke patients. Early treatment initiation is recommended for optimal outcomes.
Area of Science:
- Neurorehabilitation
- Robotics in Medicine
- Movement Science
Background:
- Ankle spasticity is a common impairment following stroke, significantly impacting functional mobility.
- Restoring motor control and gait is a primary goal in post-stroke rehabilitation.
Purpose of the Study:
- To evaluate the efficacy of traditional rehabilitation (TR) combined with a reinforced feedback virtual environment (RFVE) in reducing ankle spasticity.
- To assess the impact of this combined therapy on gait function in stroke survivors.
Main Methods:
- A study involving 10 hemiparetic patients assessed using the Modified Ashworth Scale (MAS), Functional Ambulatory Category (FAC), and Functional Independence Measure (FIM).
- Intervention comprised 1 hour/day of TR and 1 hour/day of RFVE for 3 weeks (15 sessions).
Main Results:
- Significant improvements were observed in MAS (spasticity) and FAC (gait function) scores (P < 0.05).
- Functional Independence Measure (FIM) scores showed a trend towards improvement but did not reach statistical significance (P=0.066).
- Earlier initiation of treatment correlated with greater improvements in FAC scores.
Conclusions:
- The combination of TR and RFVE demonstrates promising results for reducing spasticity and enhancing gait in stroke patients.
- Early intervention is crucial, and larger studies with diverse assessment tools are warranted.
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