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Updated: Dec 30, 2025

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Published on: August 1, 2010

Fetal intrapericardial teratomas.

Shi-Min Yuan¹, Hong Lin²

¹Departments of Cardiothoracic Surgery, The First Hospital of Putian, Teaching hospital, Fujian Medical University, Putian, Fujian Province, China.

The Turkish Journal of Pediatrics

|January 18, 2020

Summary

This summary is machine-generated.

Fetal intrapericardial teratomas are rare but can be life-threatening. Early diagnosis and intervention, including prenatal procedures and postnatal surgery, offer promising outcomes for affected newborns.

Keywords:

Pericardial teratoma fetal surgery fetus hydrops

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Area of Science:

Perinatology
Pediatric Surgery
Fetal Medicine

Background:

Fetal intrapericardial teratomas are rare tumors.
They can cause life-threatening complications like cardiac tamponade and cardiorespiratory distress.

Purpose of the Study:

To review the clinical features, management, and prognoses of fetal intrapericardial teratomas.
Provide an overview based on a literature search of the past two decades.

Main Methods:

Comprehensive literature retrieval on fetal intrapericardial teratomas.
Analysis of clinical features, gestational age at detection, tumor growth, interventions, and outcomes.

Main Results:

Tumors detected from 21-week gestation; effusions/ascites from 19-week.
Over half showed tumor growth; most required prenatal and postnatal interventions.
Fetoneonatal mortality was one-third; neonatal survival rate was 59.4%.

Conclusions:

Prenatal diagnosis and intervention, including pericardiocentesis and shunts, are crucial for hemodynamic stability.
Postnatal tumor resection is curative.
While risks are significant, outcomes are becoming more promising with timely management.