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Iron Deficiency Causes Wrinkles in Host-Commensal Relationships
1Department of Microbiome Science, Max Planck Institute for Developmental Biology, Tübingen 72076, Germany.
Abstract:
Iron is essential for both the host and its resident microbes, resulting in competition under iron-deficient conditions. However, the molecular details underlying this competition are not fully understood. In this issue, Das et al. (2019) describe how a common gut commensal disrupts the host iron regulatory pathway to prevent uptake when iron is scarce.
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