Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lithium: effects on subjective functioning and morphine-induced euphoria.

D R Jasinski, J G Nutt, C A Haertzen

    Science (New York, N.Y.)
    |February 11, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Case Studies in Neuroscience: A dissociation of balance and posture demonstrated by camptocormia.

    Journal of neurophysiology·2017
    Same author

    Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson Disease: a randomized clinical trial.

    BMC neurology·2015
    Same author

    Mobility, mood and site of care impact health related quality of life in Parkinson's disease.

    Parkinsonism & related disorders·2013
    Same author

    5-HT3 receptor antagonism and psychoactivity.

    Journal of psychopharmacology (Oxford, England)·2012
    Same author

    The effects of children on divorce and re-marriage: a multivariate analysis of life table probabilities.

    Population studies·2011
    Same author

    A meta-regression of the long-term effects of deep brain stimulation on balance and gait in PD.

    Neurology·2010
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    Lithium alone reduced euphoria in opiate addicts. However, it did not block morphine-induced euphoria, suggesting lithium

    Area of Science:

    • Neuroscience
    • Psychopharmacology
    • Addiction Research

    Background:

    • Lithium is a mood stabilizer used for bipolar disorder.
    • Its efficacy in mania suggests potential for blocking drug-induced euphoria.
    • A common final pathway for mood elevation is hypothesized.

    Purpose of the Study:

    • To investigate lithium's effect on drug-induced euphoria.
    • To determine if lithium can block morphine-induced euphoria in humans.

    Main Methods:

    • Study conducted on drug-free opiate addicts.
    • Administration of lithium alone.
    • Assessment of lithium's antieuphoric effects.
    • Evaluation of lithium's ability to block morphine-induced euphoria.

    Related Experiment Videos

    Main Results:

    • Lithium alone demonstrated antieuphoric properties in participants.
    • Lithium did not inhibit or block the euphoric effects of morphine.

    Conclusions:

    • Lithium possesses intrinsic antieuphoric effects in individuals with opiate addiction.
    • Lithium does not appear to block the euphoric effects of opioids like morphine.