Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Research02:20

Longitudinal Research

13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

506
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
506
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Long-term Colorectal Cancer Incidence After Adenoma Removal And The Effects Of Surveillance On Incidence: A Multicentre, Retrospective, Cohort Study.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Long-term Colorectal Cancer Incidence After Adenoma Removal And The Effects Of Surveillance On Incidence: A Multicentre, Retrospective, Cohort Study.

Related Experiment Video

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

591

Long-term colorectal cancer incidence after adenoma removal and the effects of surveillance on incidence: a multicentre, retrospective, cohort study.

Amanda J Cross1, Emma C Robbins2, Kevin Pack2

  • 1Cancer Screening and Prevention Research Group (CSPRG), Department of Surgery and Cancer, Imperial College London, London, UK amanda.cross1@imperial.ac.uk.

Gut
|January 19, 2020

View abstract on PubMed

Summary
This summary is machine-generated.

Postpolypectomy surveillance significantly reduces colorectal cancer (CRC) risk. However, low- and intermediate-risk patients may not need surveillance, as their CRC risk is similar to the general population.

Keywords:
adenomacolonoscopycolorectal cancersurveillance

More Related Videos

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
06:01

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

9.9K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

1.2K

Related Experiment Videos

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

591
A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
06:01

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

9.9K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

1.2K

Area of Science:

  • Gastroenterology
  • Oncology
  • Public Health

Background:

  • Postpolypectomy colonoscopy surveillance is crucial for preventing colorectal cancer (CRC).
  • Current UK guidelines stratify patients into low-, intermediate-, and high-risk groups with distinct surveillance strategies.
  • Limited evidence supports the efficacy of these stratified guidelines.

Purpose of the Study:

  • To evaluate CRC incidence across different risk groups defined by UK surveillance guidelines.
  • To assess the impact of surveillance on CRC incidence within these risk strata.
  • To compare CRC incidence in post-polypectomy patients with the general population.

Main Methods:

  • A retrospective study analyzed data from 28,972 patients who underwent colonoscopy with adenoma removal across 17 UK hospitals.
  • Patients were followed up until 2016, with Cox regression used to model CRC incidence and the effects of surveillance.
  • Standardized Incidence Ratios (SIRs) compared patient CRC incidence to the general population.

    • Main Results:

    • CRC incidence per 100,000 person-years was 140 (low-risk), 221 (intermediate-risk), and 366 (high-risk).
    • A single surveillance visit reduced CRC incidence by 40%-50% across all risk groups (HRs 0.49-0.59).
    • Without surveillance, CRC risk was similar to the general population for low- and intermediate-risk groups (SIRs 0.86 and 1.16), but higher for high-risk patients (SIR 1.91).

    Conclusions:

    • Postpolypectomy surveillance effectively lowers CRC risk.
    • Low- and intermediate-risk patients without surveillance exhibit CRC incidence comparable to the general population.
    • Consideration should be given to managing select low- and intermediate-risk patients with standard screening instead of intensive surveillance.