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Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
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The effect of hyperbaric oxygenation therapy on myocardial function.
Marina Leitman1,2, Shai Efrati3,4,5, Shmuel Fuchs6,4
1Department of Cardiology, Shamir Medical Center, Zerifin, Israel. marina.leitman@gmail.com.
The International Journal of Cardiovascular Imaging
|January 19, 2020
Summary
Hyperbaric oxygen therapy (HBOT) improved cardiac function in asymptomatic patients, enhancing ejection fraction and left ventricular strain. These findings suggest HBOT may benefit patients with heart failure and systolic dysfunction.
Area of Science:
- Cardiology
- Hyperbaric Medicine
Background:
- Hyperbaric oxygen therapy (HBOT) is a recognized treatment for various conditions.
- Limited data exists on HBOT's impact on echocardiographic parameters in asymptomatic individuals.
Purpose of the Study:
- To assess the effects of HBOT on echocardiographic parameters in asymptomatic patients.
- To evaluate changes in cardiac function following a course of HBOT.
Main Methods:
- Thirty-one asymptomatic patients received 60 HBOT sessions.
- Echocardiography was performed pre- and post-HBOT, analyzing conventional and speckle tracking imaging parameters.
Main Results:
- Ejection fraction (EF) increased significantly (p=0.02).
- Left ventricular end-systolic volume (LVESV) decreased (p=0.01), and myocardial performance index (MPI) improved (p=0.03).
- Global longitudinal strain and LV twist increased, particularly in apical segments (p<0.05).
Conclusions:
- HBOT shows potential to improve left ventricular function and cardiac performance in asymptomatic individuals.
- Further research is warranted to confirm HBOT's role in managing heart failure and systolic dysfunction.
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