Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

COPD: Management Using Bronchodilators and Corticosteroids

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nonoperative Management of a Pediatric Blunt Traumatic Distal Tracheal Injury.

Case reports in pediatrics·2026

Same author

Spatial transcriptomics reveals compartment-specific cytotoxic T cell crosstalk with AT2 and goblet cells in advanced COPD.

Biomarker research·2026

Same author

Hand in glove: New imaging techniques and airway endoscopy.

Paediatric respiratory reviews·2026

Same author

Phenotyping bronchopulmonary dysplasia using magnetic resonance imaging.

Paediatric respiratory reviews·2026

Same author

Blood vessels as primary site of rejection in murine lung transplantation.

Transplant international : official journal of the European Society for Organ Transplantation·2026

Same author

Lung mucus burden and treatment response assessed by MRI in the post-modulator era.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Search research articles

Related Experiment Video

Updated: Dec 30, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Lung MRI as a Potential Complementary Diagnostic Tool for Early COPD.

Francesca Polverino¹, Erik B Hysinger², Nishant Gupta³

¹Asthma and Airway Disease Research Center, Department of Medicine, University of Arizona, Tucson; Lovelace Respiratory Research Institute, Albuquerque, NM.

The American Journal of Medicine

|January 20, 2020

Summary

Lung MRI with hyperpolarized gas can diagnose early-onset chronic obstructive pulmonary disease (COPD) in young adults with bronchopulmonary dysplasia. This imaging technique aids in identifying lung abnormalities for better patient classification and monitoring.

Keywords:

BPD Early COPD FEV(1)Lung MRI Prematurity

More Related Videos

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Related Experiment Videos

Last Updated: Dec 30, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Area of Science:

Pulmonary Medicine
Diagnostic Imaging

Background:

Chronic obstructive pulmonary disease (COPD) is typically considered a disease of older adults.
Early-stage COPD in young adults, particularly those with bronchopulmonary dysplasia, remains understudied due to a lack of sensitive, noninvasive diagnostic tools.

Observation:

This study utilized lung magnetic resonance imaging (MRI) with hyperpolarized gas.
The imaging was employed in the diagnostic workup for bronchopulmonary dysplasia.

Findings:

The technique successfully identified chronic airflow limitation meeting spirometry criteria for early-onset COPD.
Lung MRI with hyperpolarized gas provides a noninvasive method to assess functional declines.

Implications:

This approach enables classification of young COPD patients based on both airflow limitation and imaging-detected lung abnormalities.
It supports regular, longitudinal follow-up using safe and comprehensive imaging technologies.
Advances in diagnostic imaging are crucial for managing the increasing number of young adults diagnosed with COPD.