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Updated: Dec 30, 2025

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Microsurgical Nuances of Clipping a Large Thrombosed Aneurysm with Intraoperative Dome Incision and Ultrasonic
Santiago Gomez-Paz1, Christopher M Putman2, Ajith J Thomas1
1Neurosurgery Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
We present the case of a 64-year-old male with a 5-day history of headaches. Magnetic resonance angiography revealed a 15 mm × 15 mm diameter aneurysm in the left middle cerebral artery arising in the region of the first branch of the middle cerebral artery-second branch of the middle cerebral artery (M2) bifurcation. Angiography revealed the lesion arose from the M2 vessel that contained a large amount of thrombus. Follow-up magnetic resonance angiography at 2 months revealed an enlargement of the lesion (16 mm × 17 mm), while a follow-up angiogram showed a decrease in the filling component of the lesion, suggesting further thrombosis. Given its rapid growth, endovascular and surgical options were considered and microsurgery was decided on. The aneurysm was accessed through the Sylvian fissure, and the M2 vessel was identified at the neck of the lesion where it entered and exited. We performed an intraaneurysmal thrombus evacuation to make the lesion clippable.1,2 We used a No. 11 blade and opened the dome away from the neck. Through this 3- to 4-mm incision, we inserted the tip of the ultrasonic aspirator device and used it to evacuate the thrombus in a circumferential fashion. This allowed for wall-to-wall apposition when deploying the aneurysm clip. A Sugita 15-mm clip (Mizuho America Inc., Los Angeles, California, USA) was used to obliterate the lesion. Both microvascular ultrasound and intraoperative angiography were used to confirm patency and flow distal to the aneurysm. In Video 1, we narrate the case and essential details of this approach. Neither Institutional Review Board nor patient consent was required to report this case with no identifiable patient information.
Insights
A rapidly growing middle cerebral artery (MCA) aneurysm with significant thrombus was successfully treated with microsurgery. This involved intraaneurysmal thrombus evacuation and clipping, ensuring distal vessel patency.
Area of Science:
- Neurosurgery
- Vascular Neurology
- Interventional Neuroradiology
Background:
- Aneurysms in the middle cerebral artery (MCA) bifurcation pose significant treatment challenges.
- Thrombosed aneurysms may exhibit rapid growth and require timely intervention.
- The M2 segment of the MCA is a common site for intracranial aneurysms.

