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Museum Epigenomics: Charting the Future by Unlocking the Past
Erin E Hahn1, Alicia Grealy1, Marina Alexander1
1National Research Collections Australia, Commonwealth Scientific Industrial Research Organisation, Canberra, ACT 2601, Australia.
Trends in Ecology & Evolution
|January 21, 2020
Summary
Museum specimens offer valuable epigenomic data to study gene regulation changes linked to environmental shifts. A new collaborative framework can overcome challenges in museum epigenomics research.
Area of Science:
- Genomics
- Environmental Science
- Museum Studies
Background:
- The Anthropocene is characterized by rapid environmental change.
- Epigenomic information can reveal how organisms adapt to environmental pressures.
- Museum specimens contain valuable biological samples for historical research.
Purpose of the Study:
- To explore the potential of museum specimens for epigenomic research.
- To identify challenges in museum epigenomics.
- To propose a collaborative framework for researchers and curators.
Main Methods:
- Review of existing literature on epigenomics and museum collections.
- Analysis of potential epigenetic markers in preserved tissues.
- Development of a collaborative framework model.
Main Results:
- Epigenomic information is preserved in museum specimens.
- Challenges include DNA degradation and standardization of protocols.
- A framework for collaboration between scientists and museum professionals is proposed.
Conclusions:
- Museum specimens are a valuable resource for understanding long-term gene regulation changes.
- Collaboration is essential to overcome technical and logistical hurdles in museum epigenomics.
- This field offers unique insights into adaptation during the Anthropocene.
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