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Relationship between Measurement Errors in Myocardial T1 Mapping and Heart Rate
Yasuo Amano1, Yuko Omori1, Fumi Yanagisawa1
1Department of Radiology, Nihon University Hospital.
Summary
Myocardial T1 mapping using Modified Look-Locker inversion recovery (MOLLI) shows more errors in patients with lower heart rates (bradycardia). Careful measurement is needed during MOLLI scans for these patients.
Area of Science:
- Cardiovascular Magnetic Resonance Imaging
- Quantitative MRI Techniques
Background:
- Modified Look-Locker inversion recovery (MOLLI) is a common technique for myocardial T1 mapping.
- While MOLLI is generally robust, especially during tachycardia, measurement errors can occur.
Purpose of the Study:
- To investigate the relationship between heart rate (HR) and measurement errors in myocardial T1 mapping using a confidence map.
- To assess if lower heart rates are associated with increased T1 mapping inaccuracies.
Main Methods:
- Sixty-nine male patients with normal native T1 values underwent 5s(3s)3s MOLLI scanning.
- Measurement errors in the septal myocardium were graded by observers using a confidence map (0-3 scale).
- Error scores were compared with instantaneous heart rate (iHR) parameters and left ventricular ejection fraction (LVEF).
Main Results:
- Patients with greater than score 1 measurement errors showed significantly lower minimum iHR compared to those with score 1 or less (49.8 ± 10.1 vs. 59.6 ± 9.7 bpm).
- Higher error scores correlated with lower minimum instantaneous heart rates during the MOLLI scan.
Conclusions:
- A confidence map can identify increased measurement errors in myocardial T1 mapping associated with lower minimum heart rates.
- Clinicians should exercise caution when interpreting myocardial T1 values obtained during MOLLI scans in patients with bradycardia.
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