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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

231
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
231
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

385
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
385

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Related Experiment Video

Updated: Dec 30, 2025

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
06:46

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis

Published on: January 16, 2013

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[NON-SPECIFIC GRANULOMATOUS PROSTATITIS: A CASE REPORT].

Hiroki Takizawa1, Tadashi Tabei1, Tetsuo Fukuda1

  • 1Department of Urology, Yokosuka-Kyosai Hospital.

Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|January 21, 2020
PubMed
Summary

We describe a rare case of non-specific granulomatous prostatitis that mimicked prostate cancer. Early histopathological diagnosis is crucial to avoid unnecessary radical prostatectomy for this benign condition.

Keywords:
granulomatous prostatitisprostate biopsyprostate cancer

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Area of Science:

  • Urology
  • Pathology
  • Radiology

Background:

  • Non-specific granulomatous prostatitis is a rare inflammatory condition.
  • It can present with symptoms mimicking prostate cancer, leading to diagnostic challenges.

Observation:

  • A 58-year-old man presented with symptoms of acute bacterial prostatitis but remained symptomatic despite antibiotic treatment.
  • Physical examination revealed prostatic nodules and irregularity, and MRI suggested prostate cancer.
  • Initial biopsies showed only inflammation, but further procedures revealed granulomatous prostatitis.

Findings:

  • Microscopic examination confirmed non-specific granulomatous prostatitis, with no evidence of malignancy.
  • Magnetic resonance imaging (MRI) showed significant prostate shrinkage three months post-diagnosis.
  • The patient experienced a good prognosis, characteristic of this inflammatory disease.

Implications:

  • Differentiating granulomatous prostatitis from prostate cancer is challenging using clinical and imaging methods.
  • Preoperative histopathological diagnosis is vital to prevent misdiagnosis and avoid potentially unnecessary radical prostatectomies.
  • This case highlights the importance of accurate diagnosis for appropriate patient management and prognosis.