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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Pediatric cancers in Bihar: A retrospective tertiary cancer center study
Avinash Pandey1, Anjana Singh1, Vijendra Kumar2
1Department of Medical Oncology, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
Insights
Pediatric cancers in Bihar show a higher incidence in males. Acute lymphoblastic leukemia (ALL) and Hodgkin
Area of Science:
- Pediatric Oncology
- Cancer Epidemiology
- Clinical Audit
Background:
- Limited data exists on pediatric cancer distribution in Bihar.
- Understanding cancer patterns is crucial for targeted interventions.
Purpose of the Study:
- To identify and analyze the demographic data, types, and distribution patterns of pediatric cancers in Bihar.
- To provide a comprehensive overview of the pediatric cancer landscape in the region.
Main Methods:
- Retrospective clinical audit of pediatric cancer patients (0-18 years) from January 2018 to December 2018.
- Data collected included age, sex, and cancer type, stratified into hematolymphoid and solid tumor cohorts.
- Statistical analysis using SPSS version 17.0 for frequency distribution and descriptive statistics.
Main Results:
- A total of 247 pediatric cancers were registered.
- Hematolymphoid cancers (57%) were more common than solid cancers (43%).
- Acute lymphoblastic leukemia (ALL) was the most frequent cancer (31%), followed by Hodgkin's lymphoma (19% of hematolymphoid).
- Among solid tumors, Wilms' tumor (27%), Ewing's sarcoma (15%), and germ cell tumors (14%) were most common.
Conclusions:
- Acute lymphoblastic leukemia (ALL) and Hodgkin's lymphoma are the predominant pediatric hematolymphoid malignancies.
- Wilms' tumor, Ewing's sarcoma, and germ cell tumors are the most common solid pediatric cancers in Bihar.
Background:
There is lack of information regarding pattern of distribution of pediatric cancers in Bihar. Aim: The aim of this study is to identify the pattern of distribution of pediatric cancers.
Objectives:
To analyze demographic data, type, and pattern of pediatric cancers in Bihar by retrospective clinical audit.
Materials And Methods:
All individual consecutive patients between ages 0 and 18 years registered in the Department of Medical and Pediatric Oncology from January 1, 2018 till December 31, 2018, were enrolled in this study. Data pertaining to age, sex, and type of cancer were retrieved from clinical database by retrospective audit and stratified into hematolymphoid and solid pediatric cancer cohorts. Frequency distribution and descriptive statistics were used to analyze the data using SPSS version 17.0.
Results:
A total of 247 pediatric cancers were registered, of which 142/247 (57%) and 15/247 (43%) were pediatric hematolymphoid and solid cancers, respectively. The median age was 9 years, while male-to-female ratio was 2.26. Acute lymphoblastic leukemia (ALL), 76/247 (31%) was the most common pediatric cancer overall. Hodgkin's lymphoma, 27/142 (19%) was the second most common hematolymphoid malignancy, after ALL was 76/142 (54%). Among solid tumors, Wilms' tumor was the most common, 28/105 (27%) followed by Ewing's sarcoma, 16/105 (15%), and germ cell tumor, 15/105 (14%). Central nervous system malignancies were among the least common solid tumor cancers, 3/105 (3%).
Conclusion:
ALL and Hodgkin's lymphoma are the most common pediatric cancers. Among solid malignancies, Wilms tumor, Ewing's sarcoma, and Germ cell tumor are predominant.
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