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Updated: Dec 30, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
(Diacetoxyiodo)benzene-Mediated C-H Oxidation of Benzylic Acetals
Hasil Aman1, Yen-Hsiang Wang1, Gary Jing Chuang1
1Department of Chemistry, Chung Yuan Christian University, Chung-Li 32023, Taiwan.
Abstract:
A useful oxidation of C-H bond of benzylic acetals has been achieved. This method avoids the use of stoichiometric metals and is compatible with the presence of both electron-donating and electron-withdrawing substituents on the aromatic ring. Oxidation was carried out by rapid microwave irradiation of benzylic acetals with PhI(OAc)2 as the oxidant. This led to the oxidation of acetals into 2-acetoxy-1,3-dioxolanes. Furthermore, this transformation protocol encompasses a wide range of valuable conversions of these useful synthons into different carboxylic acid derivatives.
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