Genetic polymorphism of 20 autosomal short tandem repeats (STRs) in Himachal Pradesh population, India
Related Experiment Video
Updated: Dec 30, 2025

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
Published on: July 17, 2021
Vivek Sahajpal1, Abhishek Singh2,3, Mukesh Thakur4
1State Forensic Science Laboratory, Directorate of Forensic Services, Junga, Shimla, Himachal Pradesh, 171218, India. viveksahajpal@gmail.com.
Abstract:
Genetic diversity indices and forensic parameters at 20 autosomal short tandem repeat (STR) loci were evaluated in 233 unrelated individuals of Himachal Pradesh, India. In total, 255 alleles were observed with an average of 11.25 ± 0.88 alleles per locus. None of the loci deviated from Hardy Weinberg Equilibrium. The most polymorphic and discriminative locus was Penta E. The combined power of exclusion and the combined power of discrimination were found to be 0.99 and 1. Additionally, the genetic relationship of the Himachal Pradesh population with the populations of the neighboring state was also investigated. All the STR loci were found polymorphic, and the select panel of STRs was found suitable for population genetic studies and forensic analysis.
More Related Videos
10:27Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
07:26High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
Published on: July 18, 2017
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Genetic Variation
Genes exist in different versions called alleles,...
What is Population Genetics?
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Mutation, Gene Flow, and Genetic Drift