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Pain level between clear aligners and fixed appliances: a systematic review
Paula Coutinho Cardoso1, Daybelis Gonzalez Espinosa1, Paulo Mecenas1
1Federal University of Pará (UFPA), Belém, Pará, Brazil.
Progress in Orthodontics
|January 21, 2020
Summary
Orthodontic patients using clear aligners like Invisalign reported less pain initially compared to those with fixed braces. However, this pain difference diminished within the first few days of treatment.
Area of Science:
- Orthodontics
- Dental Pain Management
- Biomaterials in Dentistry
Background:
- Pain is a significant factor influencing patient satisfaction and compliance in orthodontic treatment.
- Clear aligners offer an aesthetic alternative to traditional fixed appliances, but their impact on patient-reported pain requires thorough investigation.
Purpose of the Study:
- To compare pain levels experienced by patients undergoing orthodontic treatment with clear aligners versus fixed appliances.
- To synthesize current evidence on the differences in pain perception between these two orthodontic modalities.
Main Methods:
- A comprehensive electronic literature search was conducted across multiple databases until February 2019.
- Included studies were comparative, assessing pain between clear aligners and fixed appliances, with risk of bias and evidence levels evaluated.
- Seven studies, including one randomized clinical trial, were included; meta-analysis was precluded by heterogeneity.
Main Results:
- Most studies indicated lower initial pain with Invisalign compared to conventional fixed appliances.
- These pain differences were not sustained beyond the initial days of treatment.
- No comparable evidence was found for other clear aligner brands.
Conclusions:
- Orthodontic patients treated with Invisalign may experience reduced pain during the initial days compared to fixed appliances.
- Pain levels become comparable between the two methods after the initial phase and up to three months.
- While pain is a consideration, treatment predictability and outcomes are paramount, especially given the transient nature of pain differences.

