Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

767
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
767
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

279
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
279
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism01:18

Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism

2.6K
Birch reduction uses solvated electrons as reducing agents. The reaction converts benzene to 1,4-cyclohexadiene. The reaction proceeds by the transfer of a single electron to the ring to form a benzene radical anion. This anion is highly basic—it abstracts a proton from the alcohol to form a cyclohexadienyl radical. Another single electron transfer gives the cyclohexadienyl anion. A proton transfer from the alcohol forms 1,4-cyclohexadiene. Since this reduction occurs via radical anion...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Divergent mechanisms of active antibiotic resistance gene enrichment in soil driven by pesticide diversity.

Nature communications·2026
Same author

Hyperacute Rejection of a Kidney Allograft Associated with Anti-Histidyl-tRNA Synthetase and Anti-Signal Transducer and Activator of Transcription 6 Antibodies.

Kidney international reports·2026
Same author

3D-printed MOF-hydrogel microarray for multiplexed miRNA detection and early herb-induced liver injury warning.

Biosensors & bioelectronics·2026
Same author

Dynamic Quantum Gate Based on Controllable Chiral Liquid Crystal Nanostructure.

Nano letters·2026
Same author

Facile preparation of a dual-readout metal-organic framework with aggregation-induced emission for highly sensitive detection of GST-α and Fe<sup>2</sup>.

Chemical communications (Cambridge, England)·2026
Same author

Reconfigurable ferroelectric chiral nanostructures enable fast-switchable optical spatial differentiation.

Light, science & applications·2026

Related Experiment Video

Updated: Dec 30, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.4K

Recent progress on donor and donor-donor carbenes.

Dong Zhu1, Lianfen Chen, Hanlin Fan

  • 1Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, P. R. China. zhusf@scut.edu.cn.

Chemical Society Reviews
|January 21, 2020
PubMed
Summary

Donor and donor-donor carbene chemistry has rapidly advanced, offering efficient methods for creating C-C and C-X bonds in organic synthesis. This review details recent developments and applications in synthesizing complex molecules.

More Related Videos

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
14:07

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus

Published on: October 3, 2014

14.1K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.9K

Related Experiment Videos

Last Updated: Dec 30, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.4K
Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
14:07

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus

Published on: October 3, 2014

14.1K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.9K

Area of Science:

  • Organic Chemistry
  • Synthetic Chemistry

Background:

  • Donor and donor-donor carbenes are crucial reactive intermediates in organic synthesis.
  • Their chemistry has seen significant growth and development over the last two decades.

Purpose of the Study:

  • To provide a comprehensive review of recent advancements in donor and donor-donor carbene chemistry.
  • To highlight the utility of these carbenes in forming carbon-carbon and carbon-heteroatom bonds.

Main Methods:

  • Review of literature focusing on carbene precursors like diazo compounds, hydrazones, enynones, cycloheptatrienes, and cyclopropenes.
  • Discussion of typical transformations and reaction mechanisms.
  • Analysis of applications in synthesizing complex natural products and bioactive molecules.

Main Results:

  • Donor and donor-donor carbene chemistry enables efficient protocols for C-C and C-X bond formation.
  • Diverse carbene precursors facilitate a wide range of synthetic transformations.
  • These methods are valuable for constructing complex molecular architectures.

Conclusions:

  • This review offers a timely and thorough overview of the progress in donor and donor-donor carbene chemistry.
  • The field continues to expand, providing powerful tools for synthetic organic chemists.
  • Future research is expected to further leverage these carbene species for novel synthetic strategies.