Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

507
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
507
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

644
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
644
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

404
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
404
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

844
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
844
Hypertension I: Introduction01:28

Hypertension I: Introduction

601
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
601
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers01:26

Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers

386
Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
386

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Encoding of modality-specific face engrams promotes distinct recruitment of mnemonic processing mechanisms: A mobile-EEG study comparing encoding and retrieval of 2D and 3D avatars under virtual reality conditions.

NeuroImage·2026
Same author

Brain Evoked Response Qualification Using Multi-Set Consensus Clustering: Toward Single-Trial EEG Analysis.

Brain topography·2024
Same author

Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney.

Blood pressure·2024
Same author

Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire.

Journal of hypertension·2024
Same author

One body, two faces: How double standards influence body evaluation in women with binge-eating disorder compared to mentally healthy women with higher weight and average weight.

The International journal of eating disorders·2023
Same author

[Psychometric Evaluation of the German-Language Version of the Feedback on Physical Appearance Scale on Female Adolescents With Eating Disorders Plus Adolescents and Women Without Eating Disorders].

Psychotherapie, Psychosomatik, medizinische Psychologie·2021

Related Experiment Video

Updated: Dec 30, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

3.9K

[Therapy Resistant and Refractory Hypertension].

Rainer Düsing

    Deutsche Medizinische Wochenschrift (1946)
    |January 21, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Resistant hypertension is diagnosed when blood pressure remains high despite medication. Differentiating true resistance from apparent resistance is crucial for effective treatment strategies in hypertensive patients.

    More Related Videos

    Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
    04:37

    Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

    Published on: June 6, 2025

    600
    Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
    05:57

    Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

    Published on: May 17, 2024

    1.1K

    Related Experiment Videos

    Last Updated: Dec 30, 2025

    Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
    08:35

    Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

    Published on: May 26, 2022

    3.9K
    Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
    04:37

    Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

    Published on: June 6, 2025

    600
    Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
    05:57

    Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

    Published on: May 17, 2024

    1.1K

    Area of Science:

    • Cardiology
    • Nephrology
    • Pharmacology

    Background:

    • Resistant hypertension is defined as blood pressure uncontrolled by standard treatment.
    • Updated definitions include patients on four or more antihypertensive agents.
    • Refractory hypertension involves uncontrolled blood pressure despite five or more agents, including specific diuretics and antagonists.

    Purpose of the Study:

    • To clarify definitions of resistant hypertension.
    • To distinguish between apparent, pseudo, and true resistant hypertension.
    • To guide diagnostic and treatment strategies for resistant hypertension.

    Main Methods:

    • Review of current definitions and diagnostic criteria for resistant hypertension.
    • Emphasis on ruling out pseudo-resistance (e.g., white coat hypertension, non-adherence).
    • Proposal of using the term 'apparent resistance' before confirming 'true resistance'.

    Main Results:

    • Apparent resistant hypertension affects an estimated 10-15% of treated patients.
    • The prevalence of true resistant hypertension is unknown but likely small.
    • True resistant hypertension often involves secondary hypertension and may benefit from intensified treatment, particularly with expanded diuretic use.

    Conclusions:

    • Resistant hypertension presents a significant diagnostic challenge.
    • Accurate identification of true resistant hypertension is essential for appropriate management.
    • Focus should be on differentiating true resistance and identifying secondary causes of hypertension.