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A Validation Study: How Predictive Is a Diagnostic Coding Algorithm at Identifying Rheumatic Heart Disease in Western
Jordan Ashlea Fitz-Gerald1, Chris Olivia Ongzalima1, Andre Ng1
1Medical School, University of Western Australia, Perth, WA, Australia.
An expert algorithm improves rheumatic heart disease (RHD) case identification using hospital codes. It shows high accuracy in high-risk populations and for probable RHD diagnoses.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- International Classification of Diseases (ICD-10) codes for rheumatic heart disease (RHD) lack specificity.
- Existing codes (I05-I08) include unspecified valvular heart disease, hindering accurate RHD burden estimation.
- An expert-developed algorithm was created to enhance RHD epidemiological case ascertainment.
Purpose of the Study:
- To evaluate the positive predictive value (PPV) of hospital admissions identified by an expert algorithm for RHD.
- To compare the algorithm's accuracy across different population risk groups, age demographics, and coding classifications.
Main Methods:
- Chart reviews of 368 RHD-coded hospital admissions in Western Australia (2009-2016).
- Selection of cases based on algorithm-positive codes from high-risk RHD populations and a random sample from low-risk groups.
- RHD diagnosis confirmation via echocardiography or clinical records; PPVs compared across various patient and coding strata.
Main Results:
- High-risk patients demonstrated significantly higher PPVs (83.8%) compared to low-risk patients (54.9%).
- Algorithm-defined 'probable RHD' codes yielded higher PPVs (91.5%) than 'possible' codes (51.5%).
- In low-risk groups, principal diagnoses had higher PPVs (84.5%) than secondary diagnoses (44.8%).
Conclusions:
- The algorithm is effective for identifying RHD when coded as a principal diagnosis, using 'probable' codes, or in high-risk populations.
- Further refinement of the algorithm is necessary to improve the accuracy of RHD identification in low-risk patient groups.
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