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In-vitro Mutagenesis01:16

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Related Experiment Video

Updated: Dec 30, 2025

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer

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Author Correction: Engineering a humanized telomerase reverse transcriptase gene in mouse embryonic stem cells.

De Cheng1, Yuanjun Zhao2, Fan Zhang1

  • 1Department of Pharmaceutical Sciences, Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington, USA.

Scientific Reports
|January 22, 2020
PubMed
Summary
This summary is machine-generated.

This study has been amended. Please refer to the updated version for the most current findings and analysis.

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Area of Science:

  • Not specified in the abstract.

Context:

  • The original paper has been updated.
  • An amendment is available for review.

Purpose:

  • To provide corrected or additional information.
  • To ensure the accuracy of the published research.

Summary:

  • The authors have issued a formal amendment to this publication.
  • This amendment contains revisions to the original content.

Impact:

  • Readers should consult the amendment for the definitive version of the paper.
  • Ensures access to the most accurate scientific record.