Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Chemical Profile and Biological Activities of <i>Eryngium dichotomum</i>: UHPLC-MS/NMR Characterization, and In Vitro Antioxidant Activity Along with the Antitumor Effect of Falcarinol.

Molecules (Basel, Switzerland)·2026
Same author

Bioplastics Toxicity upon Ingestion: A Critical Review of Biotransformation and Gastrointestinal Effects.

Polymers·2026
Same author

Gold Nanorods as Effective Modulators of Shape Memory Behavior in Physiological Conditions of PLA/PEG Blends.

ACS nanoscience Au·2026
Same author

Thiourea-formaldehyde-Functionalized Graphene Oxide for the Selective Removal of Copper from Multielement Solution.

ACS omega·2026
Same author

Lipid Saturation and Cholesterol Drive the Mechanical Response of Lipid Bilayer to Ionic Liquid: An Atomic Force Microscopy Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Upconversion Nanoparticles with Mesoporous Silica Coatings for Doxorubicin Targeted Delivery to Melanoma Cells.

Molecules (Basel, Switzerland)·2026

Related Experiment Video

Updated: Dec 30, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

12.3K

Biocompatible chitosan-based composites with properties suitable for hyperthermia therapy.

Ana Barra1, Zélia Alves1, Nuno M Ferreira2

  • 1CICECO - Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal. claudianunes@ua.pt pcferreira@ua.pt.

Journal of Materials Chemistry. B
|January 22, 2020
PubMed
Summary

This study introduces novel chitosan-based bionanocomposites with reduced graphene oxide-iron oxide filler. These flexible, biocompatible materials show promise for biomedical applications like magnetic hyperthermia treatments.

More Related Videos

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
10:23

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics

Published on: December 1, 2023

870
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Related Experiment Videos

Last Updated: Dec 30, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

12.3K
Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
10:23

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics

Published on: December 1, 2023

870
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Nanotechnology

Background:

  • Flexible and biocompatible composites are crucial for advanced biomedical applications.
  • Chitosan-based materials offer a sustainable and versatile platform for developing novel composites.
  • There is a need for multifunctional materials with tunable properties for targeted therapies.

Purpose of the Study:

  • To develop flexible and multifunctional chitosan-based bionanocomposites.
  • To incorporate a mixed reduced graphene oxide-iron oxide (rGO-Fe3-xO4) filler into a chitosan matrix.
  • To evaluate the superparamagnetic, antioxidant, mechanical, and biocompatibility properties for biomedical potential.

Main Methods:

  • One-pot synthesis of the rGO-Fe3-xO4 filler.
  • Solvent casting method for creating chitosan bionanocomposite films.
  • Characterization of superparamagnetic response, antioxidant activity, mechanical strength, and cytotoxicity.

Main Results:

  • The bionanocomposites exhibit superparamagnetic behavior at room temperature.
  • Antioxidant activity was enhanced ninefold compared to pristine chitosan.
  • Mechanical properties were tunable, ranging from elastic to stiff films (8 MPa to 285 MPa).
  • Magnetic hyperthermia tests showed a significant temperature increase (40 °C in 45 s).
  • No cytotoxicity was observed in the nontumorigenic HaCat cell line.

Conclusions:

  • The developed chitosan-based bionanocomposites are flexible, biocompatible, and multifunctional.
  • The rGO-Fe3-xO4 filler enhances antioxidant and mechanical properties.
  • These materials show significant potential for biomedical applications, particularly in magnetic hyperthermia treatments.