Pansystolic murmur in the newborn: tricuspid regurgitation versus ventricular septal defect

Neonates with a pansystolic murmur who had Doppler echocardiography were reviewed. Ten infants had tricuspid regurgitation (detected at a mean age of 25 hours), 12 had a ventricular septal defect (detected at 65 hours), and seven had both. Tricuspid regurgitation is the more likely cause of a pansystolic murmur at the lower left sternal border in the first day of life.