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Updated: Dec 30, 2025

Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
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Initial Management of Incarcerated Pregnant Women With Opioid Use Disorder

Alane O'Connor1, Nathaniel Bowling1

  • 1Maine-Dartmouth Family Medicine Residency, Maine General Medical Center, Waterville, ME, USA.

Journal of Correctional Health Care : the Official Journal of the National Commission on Correctional Health Care
|January 22, 2020
PubMed

The epidemic of opioid and other drug use and related arrests are a growing public health crisis in the United States. The national prevalence of pregnant women with opioid use disorder (OUD) has increased dramatically from 1.5 per 1,000 delivery hospitalizations in 1999 to 6.5 in 2014. The combination of these factors has led to an increased frequency of pregnant women with OUDs in the correctional health care system. This protocol provides evidence-based treatment recommendations including the initiation of methadone and buprenorphine in the inpatient or jail setting. It also explores many of the nuances around caring for this vulnerable patient population and discusses ways in which the medical and correctional health care teams can efficiently collaborate to improve patient outcomes.

Keywords:
buprenorphineincarcerationmedication-assisted treatmentmethadoneopioid use disorder

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