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Updated: Aug 3, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release
Chun-Nan Zhu1, Liu-Yuan Zang, Dong-Yun Zheng
1College of Biomedical Engineering, Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment, and Key Laboratory of Cognitive Science (State Ethnic Affairs Commission), South-Central University for Nationalities, Wuhan 430074, P. R. China. cnzhu@mail.scuec.edu.cn.
Abstract:
Poor solid-tumor penetration of nanocarriers limits the drug efficacy. Herein, small-sized copolymeric nanoparticles are prepared for delivering the chemotherapeutic drug DOX into solid tumors deeply and releasing the drug effectively. These small-sized copolymeric nanoparticles represent substantial potential for clinical translation.
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