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Related Concept Videos

Infection01:20

Infection

11.5K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.5K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

4.4K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.4K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.8K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.8K
Stages of Infection01:26

Stages of Infection

64.6K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
64.6K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K

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Related Experiment Video

Updated: Dec 30, 2025

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
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Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses

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[Infectious diseases : « less is more »].

Jonathan Tschopp1, Benoît Guéry1, Noémie Boillat Blanco1

  • 1Service des maladies infectieuses, CHUV, 1011 Lausanne.

Revue Medicale Suisse
|January 22, 2020
PubMed
Summary

Early oral antibiotic switches are effective for severe bacterial infections. Emerging antibiotic resistance in Neisseria gonorrhoeae and advancements in Influenza treatment, including new antiviral drugs, necessitate updated therapeutic strategies.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Virology

Background:

  • Severe bacterial infections can benefit from early oral antibiotic therapy.
  • Emerging antimicrobial resistance, such as ceftriaxone-resistant Neisseria gonorrhoeae, poses a significant public health threat.
  • Recent outbreaks of Ebola and measles, alongside the discovery of new viruses like Alongshan virus, underscore the dynamic nature of infectious diseases.

Purpose of the Study:

  • To evaluate the safety and efficacy of early oral antibiotic switches in severe bacterial infections.
  • To review new data on dual antibiotherapy for severe Staphylococcus aureus infections.
  • To highlight the need for novel therapeutic strategies against emerging resistant pathogens and update on viral disease management.

Main Methods:

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Systemic Bacterial Infection and Immune Defense Phenotypes in Drosophila Melanogaster
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Systemic Bacterial Infection and Immune Defense Phenotypes in Drosophila Melanogaster

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  • Review of clinical data on early oral antibiotic switch strategies.
  • Analysis of recent findings on dual antibiotherapy for Staphylococcus aureus.
  • Synthesis of information on emerging infectious diseases and updated treatment guidelines.

    • Main Results:

    • Early oral antibiotic switch is demonstrated as safe and efficient in selected patients with severe bacterial infections.
    • New data support dual antibiotherapy approaches for severe Staphylococcus aureus infections.
    • Emergence of ceftriaxone-resistant Neisseria gonorrhoeae necessitates alternative treatment strategies.

    Conclusions:

    • Early oral antibiotic switching is a viable strategy for managing severe bacterial infections in appropriate patient populations.
    • Continued research and development of new therapeutic options are crucial to combat antimicrobial resistance and emerging viral threats.
    • Updated guidelines and novel treatments, such as baloxavir marboxil for Influenza, are vital for addressing current infectious disease challenges.