Related Experiment Video
Updated: Dec 30, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Bariatric Surgery in Obesity: Effects on Gut Microbiota and Micronutrient Status
Daniela Ciobârcă1, Adriana Florinela Cătoi2, Cătălin Copăescu3
1Department of Bromatology, Hygiene, Nutrition, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 23 Gheorghe Marinescu Street, 400337 Cluj-Napoca, Romania.
Abstract:
Obesity is associated with reduced gut microbial diversity and a high rate of micronutrient deficiency. Bariatric surgery, the therapy of choice for severe obesity, produces sustained weight loss and improvements in obesity-related comorbidities. Also, it significantly alters the gut microbiota (GM) composition and function, which might have an important impact on the micronutrient status as GM is able to synthesize certain vitamins, such as riboflavin, folate, B12, or vitamin K2. However, recent data have reported that GM is not fully restored after bariatric surgery; therefore, manipulation of GM through probiotics represents a promising therapeutic approach in bariatric patients. In this review, we discuss the latest evidence concerning the relationship between obesity, GM and micronutrients, the impact of bariatric surgery on GM in relation with micronutrients equilibrium, and the importance of the probiotics' supplementation in obese patients submitted to surgical treatment.
Related Concept Videos
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Anatomy of the Intestines
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Bacterial Flora of the Large Intestine
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.

