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Incidence and Risk Factors for Severe Dehydration in Hospitalized Children in Ujjain, India
Abhishek Sharma1, Aditya Mathur1, Cecilia Stålsby Lundborg2
1Department of Pediatrics, Gardi Medical College, Ujjain 456006, India.
Insights
Severe dehydration in children is linked to not being exclusively breastfed, lack of oral rehydration solution or zinc, and overcrowded living conditions. These modifiable factors highlight the need for targeted public health interventions to reduce childhood mortality.
Area of Science:
- Pediatrics
- Public Health
- Infectious Diseases
Background:
- Diarrhoea is a major global cause of illness and death in children under five.
- Severe dehydration is a critical complication of childhood diarrhoea requiring urgent medical attention.
- Identifying risk factors is crucial for developing effective preventive strategies.
Purpose of the Study:
- To identify independent risk factors associated with severe dehydration in children presenting to a tertiary care hospital.
- To analyze the role of feeding practices, pre-hospital treatment, and living conditions in severe dehydration.
Main Methods:
- A cross-sectional study conducted in Ujjain, India, involving 332 children aged 1 month to 12 years.
- Children with 'some dehydration' or 'dehydration' based on World Health Organization criteria were assessed.
- Multivariate logistic regression was used to determine independent risk factors for severe dehydration.
Main Results:
- 70% of the studied children were diagnosed with severe dehydration.
- Independent risk factors included: not exclusively breastfed in the first six months (AOR 5.67), no prior oral rehydration solution (AOR 1.34), no prior oral zinc (AOR 2.66), and overcrowded living conditions (AOR 5.52).
- Statistical significance (p < 0.001) was observed for exclusive breastfeeding, oral zinc, and living conditions.
Conclusions:
- Exclusive breastfeeding for the first six months is a critical protective factor against severe dehydration.
- Lack of access to or knowledge about oral rehydration solution and zinc supplementation increases risk.
- Overcrowded living conditions are a significant environmental risk factor, emphasizing the need for socio-environmental interventions.
Abstract:
Diarrhoea contributes significantly to the under-five childhood morbidity and mortality worldwide. This cross-sectional study was carried out in a tertiary care hospital in Ujjain, India from July 2015 to June 2016. Consecutive children aged 1 month to 12 years having "some dehydration" and "dehydration" according to World Health Organization classification were eligible to be included in the study. Other signs and symptoms used to assess severe dehydration were capillary refill time, urine output, and abnormal respiratory pattern. A questionnaire was administered to identify risk factors for severe dehydration, which was the primary outcome. Multivariate logistic regression modeling was used to detect independent risk factors for severe dehydration. The study included 332 children, with mean ± standard deviation age of 25.62 ± 31.85 months; out of which, 70% (95% confidence interval [CI] 65 to 75) were diagnosed to have severe dehydration. The independent risk factors for severe dehydration were: child not exclusive breastfed in the first six months of life (AOR 5.67, 95%CI 2.51 to 12.78; p < 0.001), history of not receiving oral rehydration solution before hospitalization (AOR 1.34, 95%CI 1.01 to 1.78; p = 0.038), history of not receiving oral zinc before hospitalization (AOR 2.66, 95%CI 1.68 to 4.21; p < 0.001) and living in overcrowded conditions (AOR 5.52, 95%CI 2.19 to 13.93; p < 0.001). The study identified many risk factors associated with severe childhood dehydration; many of them are modifiable though known and effective public health interventions.
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