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Multifunctional Hydroxyapatite Coated with Arthemisia absinthium Composites
Mariana Stefania Raita1, Simona Liliana Iconaru2, Andreea Groza3
1Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 105 Splaiul Independentei, Sector 5, 050097 Bucharest, Romania.
Molecules (Basel, Switzerland)
|January 23, 2020
Summary
This study developed a hydroxyapatite biocomposite infused with Artemisia absinthium essential oil, demonstrating significant antimicrobial properties against tested microbial strains, including Candida parapsilosis.
Area of Science:
- Biomaterials Science
- Microbiology
- Pharmacology
Background:
- Essential oils from plants exhibit known antibacterial effects.
- Hydroxyapatite is a key biomaterial with potential for infection prevention.
- Postoperative infections remain a significant clinical challenge.
Purpose of the Study:
- To develop a novel biocomposite material using hydroxyapatite coated with Artemisia absinthium essential oil.
- To evaluate the antimicrobial activity of this new biocomposite.
- To offer a low-cost, effective solution for preventing infections.
Main Methods:
- Synthesis of hydroxyapatite coated with Artemisia absinthium essential oil.
- Characterization of structural properties of the resulting biocomposite.
- Assessment of antimicrobial efficiency against various microbial strains.
Main Results:
- The Artemisia absinthium essential oil-hydroxyapatite biocomposite demonstrated strong antimicrobial effects.
- Wormwood essential oil showed particular efficacy against Candida parapsilosis.
- The observed antimicrobial properties are attributed to the essential oil component within the composite.
Conclusions:
- The developed biocomposite exhibits significant potential as an antimicrobial agent.
- Artemisia absinthium essential oil-hydroxyapatite composites offer a promising strategy for infection control.
- This cost-effective method yields a valuable biomaterial for medical applications.

